In most human solid cancer types, a high frequency of intratumoral neutrophils is associated with poor prognosis. In a recent study, Maas et al. identified an intratumoral niche in which mononuclear myeloid cells drive proinflammatory neutrophil activation in brain tumors. This study sheds new light on the intratumoral modulation of neutrophils.
Copyright © 2024 The Author. Published by Elsevier Ltd.. All rights reserved.