Malignant Peritoneal Mesothelioma Complicating Familial Mediterranean Fever on 18 F-FDG PET/CT

Clin Nucl Med. 2024 Mar 1;49(3):e123-e124. doi: 10.1097/RLU.0000000000005041. Epub 2024 Jan 24.

Abstract

A 77-year-old man with a personal history of familial Mediterranean fever presented with a slowly enlarging tumefaction of the left abdominal wall and persistent inflammatory syndrome despite good adherence to colchicine. 18 F-FDG PET/CT showed a hypermetabolic muscular mass of the abdominal wall along with other hypermetabolic lesions including a peritoneal mass and several subcutaneous soft tissue nodules. CT-guided needle biopsy led to the diagnosis of a muscular localization of a malignant peritoneal mesothelioma, which is an extremely rare complication of familial Mediterranean fever. Six courses of chemotherapy with carboplatin and pemetrexed allowed an almost complete response.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Familial Mediterranean Fever* / complications
  • Familial Mediterranean Fever* / diagnostic imaging
  • Familial Mediterranean Fever* / drug therapy
  • Fluorodeoxyglucose F18
  • Humans
  • Male
  • Mesothelioma* / complications
  • Mesothelioma* / diagnostic imaging
  • Mesothelioma, Malignant* / complications
  • Peritoneal Neoplasms* / complications
  • Peritoneal Neoplasms* / diagnostic imaging
  • Peritoneal Neoplasms* / pathology
  • Positron Emission Tomography Computed Tomography

Substances

  • Fluorodeoxyglucose F18