The integration of biology and spacefaring has led to the development of three interrelated fields: Astrobiology, Bioastronautics, and Space Bioprocess Engineering. Astrobiology is concerned with the study of the origin, evolution, distribution, and future of life in the universe, while Bioastronautics focuses on the effects of spaceflight on biological systems, including human physiology and psychology. Space Bioprocess Engineering, on the other hand, deals with the design, deployment, and management of biotechnology for human exploration. This paper highlights the unique contributions of each field and outlines opportunities for biologists to engage in these exciting avenues of research. By providing a clear overview of the major fields of biology and spacefaring, this paper serves as a valuable resource for scientists and researchers interested in exploring the integration of these disciplines.