MaDDOSY (Mass Determination Diffusion Ordered Spectroscopy) using an 80 MHz Bench Top NMR for the Rapid Determination of Polymer and Macromolecular Molecular Weight

Owen Tooley; William Pointer; Rowan Radmall; Mia Hall; Valentin Beyer; Kieran Stakem; Thomas Swift; James Town; Tanja Junkers; Paul Wilson; Daniel Lester; David Haddleton

doi:10.1002/marc.202300692

MaDDOSY (Mass Determination Diffusion Ordered Spectroscopy) using an 80 MHz Bench Top NMR for the Rapid Determination of Polymer and Macromolecular Molecular Weight

Macromol Rapid Commun. 2024 Apr;45(8):e2300692. doi: 10.1002/marc.202300692. Epub 2024 Feb 11.

Authors

Affiliations

¹ Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK.
² Department of Chemistry, University of Bradford, West Yorkshire, Bradford, BD7 1DP, UK.
³ Polymer Characterization RTP, University of Warwick, Coventry, CV4 7AL, UK.
⁴ School of Chemistry, Monash University, Box 23 Victoria, Clayton, VIC, 3800, Australia.

PMID: 38288674
DOI: 10.1002/marc.202300692

Abstract

Measurement of molecular weight is an integral part of macromolecular and polymer characterization which usually has limitations. Herein, this article presents the use of a bench-top 80 MHz Nuclear Magnetic Resonance (NMR) spectrometer for diffusion-ordered spectroscopy as a practical and rapid approach for the determination of molecular weight/size using a novel solvent and polymer-independent universal calibration.

Keywords: NMR spectroscopy; diffusion‐ordered spectroscopy; macromolecule; molecular weight; polymer.

MeSH terms

Diffusion
Macromolecular Substances* / chemistry
Magnetic Resonance Spectroscopy* / methods
Molecular Weight*
Polymers* / chemistry

Substances

Polymers
Macromolecular Substances

Abstract

MeSH terms

Substances

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