Development of a Consensus-Based List of Potential Quality Indicators for Fever and Inflammation of Unknown Origin

William F Wright; Albrecht Betrains; Lauren Stelmash; Catharina M Mulders-Manders; Chantal P Rovers; Steven Vanderschueren; Paul G Auwaerter

doi:10.1093/ofid/ofad671

Development of a Consensus-Based List of Potential Quality Indicators for Fever and Inflammation of Unknown Origin

Open Forum Infect Dis. 2024 Jan 11;11(2):ofad671. doi: 10.1093/ofid/ofad671. eCollection 2024 Feb.

Authors

William F Wright¹, Albrecht Betrains², Lauren Stelmash³, Catharina M Mulders-Manders⁴, Chantal P Rovers⁴, Steven Vanderschueren^{5

6}, Paul G Auwaerter^{1

7}

Affiliations

¹ Division of Infectious Diseases, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
² General Internal Medicine Department, University Hospitals Leuven, Leuven, Belgium.
³ Division of Infectious Diseases, Department of Medicine, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, USA.
⁴ Division of Infectious Diseases, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
⁵ General Internal Medicine Department, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
⁶ Department of Microbiology, Immunology, and Transplantation, Laboratory of Clinical Infectious and Inflammatory Disorders, KU Leuven, Leuven, Belgium.
⁷ The Sherrilyn and Ken Fisher Center for Environmental Infectious Diseases, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

Abstract

With a growing emphasis on value-based reimbursement, developing quality indicators for infectious diseases has gained attention. Quality indicators for fever of unknown origin and inflammation of unknown origin are lacking. An assembled group of international experts developed 12 quality measures for these conditions, which could be validated with additional study.

Keywords: fever of unknown origin; inflammation of unknown origin; pyrexia of unknown origin; quality indicators.