Scan-Specific Self-Supervised Bayesian Deep Non-Linear Inversion for Undersampled MRI Reconstruction

IEEE Trans Med Imaging. 2024 Jun;43(6):2358-2369. doi: 10.1109/TMI.2024.3364911. Epub 2024 Jun 5.

Abstract

Magnetic resonance imaging is subject to slow acquisition times due to the inherent limitations in data sampling. Recently, supervised deep learning has emerged as a promising technique for reconstructing sub-sampled MRI. However, supervised deep learning requires a large dataset of fully-sampled data. Although unsupervised or self-supervised deep learning methods have emerged to address the limitations of supervised deep learning approaches, they still require a database of images. In contrast, scan-specific deep learning methods learn and reconstruct using only the sub-sampled data from a single scan. Here, we introduce Scan-Specific Self-Supervised Bayesian Deep Non-Linear Inversion (DNLINV) that does not require an auto calibration scan region. DNLINV utilizes a Deep Image Prior-type generative modeling approach and relies on approximate Bayesian inference to regularize the deep convolutional neural network. We demonstrate our approach on several anatomies, contrasts, and sampling patterns and show improved performance over existing approaches in scan-specific calibrationless parallel imaging and compressed sensing.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Bayes Theorem*
  • Brain / diagnostic imaging
  • Deep Learning*
  • Humans
  • Image Processing, Computer-Assisted* / methods
  • Magnetic Resonance Imaging* / methods
  • Supervised Machine Learning