In Human Esophageal Epithelial and Muscle Cells Treated With Th2 Cytokines, Upadacitinib Decreases Eotaxin-3 Secretion and Muscle Tension

Gastroenterology. 2024 Jun;166(6):1166-1169.e3. doi: 10.1053/j.gastro.2024.02.011. Epub 2024 Feb 14.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chemokine CCL26 / genetics
  • Chemokine CCL26 / metabolism
  • Cytokines / metabolism
  • Epithelial Cells / drug effects
  • Epithelial Cells / metabolism
  • Esophagus / drug effects
  • Esophagus / immunology
  • Esophagus / metabolism
  • Heterocyclic Compounds, 3-Ring* / pharmacology
  • Humans
  • Muscle Contraction / drug effects
  • Myocytes, Smooth Muscle / drug effects
  • Myocytes, Smooth Muscle / metabolism
  • Th2 Cells / drug effects
  • Th2 Cells / immunology

Substances

  • upadacitinib
  • CCL26 protein, human