Surgical Management and System Therapy of the Most Giant Known Malignant Metastatic Breast Phyllodes Tumor: A Case Report and Review of the Literature

Oncol Res Treat. 2024;47(4):145-148. doi: 10.1159/000537956. Epub 2024 Feb 21.

Abstract

Introduction: Phyllodes tumors belong to uncommon fibroepithelial breast tumors with a range of biological behaviors. Phyllodes tumors are responsible for less than 1 percent of all neoplasms of the breast.

Case presentation: A 66-year-old woman presented to our Breastcancer Unit in March 2021 because of a huge mass of her left breast with bleeding out of a tumor necrosis. Five years ago in 2016, a benign phyllodes tumor was diagnosed externally. When we started the treatment, the tumor had a weight of 18.6 kg.

Conclusion: We describe the surgical management and the systemic treatment of metastatic disease.

Keywords: Chemotherapy; Giant tumor; Surgical management.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Aged
  • Breast Neoplasms* / surgery
  • Female
  • Humans
  • Mastectomy
  • Phyllodes Tumor* / diagnosis
  • Phyllodes Tumor* / pathology
  • Phyllodes Tumor* / surgery