Comparison of Computed Tomography Findings between Adult and Pediatric COVID-19 Patients

Curr Med Imaging. 2024:20:1-7. doi: 10.2174/0115734056248266230921072432.

Abstract

Purpose: This study aims to compare chest computed tomography (CT) findings between adult and pediatric patients with coronavirus disease-19 (COVID-19) pneumonia.

Materials and methods: This study included 30 pediatric patients aged 1 to 17 years and 30 adult patients over 18 years of age with COVID-19 pneumonia confirmed by reverse transcriptase-polymerase chain reaction (RT-PCR) who have findings related to COVID-19 on Chest Computed Tomography. The CT findings of adult and pediatric patients were compared with a z-test.

Results: Bilateral involvement (p:0.00056), involvement in all five lobes (p<0.00001), and central and peripheral involvement (p:0.01928) were significantly higher in the adult group compared to the pediatric group. In the pediatric group, the frequency of unilateral involvement (p:0.00056), involvement of solitary lobe (p:0.00132), and peripheral involvement (p: 0.01928) were significantly higher than in the adult group. The most common parenchymal finding in adults and pediatric patients was ground-glass opacities (100% and 83%, respectively). Among the parenchymal findings in adults, ground-glass opacities with consolidation (63%) were the second most common finding, followed by air bronchogram (60%) in adults, while in pediatric patients, halo sign (27%) and nodule (27%) were the second most common, followed by the ground-glass opacities with consolidation (23%).

Conclusion: The CT findings of pediatric COVID-19 patients must be well-known as the course of the disease is usually less severe, and the radiological findings are uncertain when compared with adults.

Keywords: Adult; Bronchiectasis.; COVID-19; Crazy paving pattern; Multidetector computed tomography; Pediatrics; Pneumonia; Reverse halo sign.

MeSH terms

  • Adolescent
  • Adult
  • COVID-19* / diagnostic imaging
  • Child
  • Humans
  • Pneumonia*
  • SARS-CoV-2
  • Tomography, X-Ray Computed / methods