A compact scintillator-based detector with collimator and shielding for dose monitoring in boron neutron capture therapy

Phys Imaging Radiat Oncol. 2024 Feb 16:29:100556. doi: 10.1016/j.phro.2024.100556. eCollection 2024 Jan.

Abstract

Boron neutron capture therapy exploits 10B(n,α)7Li reactions for targeted tumor destruction. In this work, we aimed at developing a dose monitoring system based on the detection of 478 keV gamma rays emitted by the reactions, which is very challenging due to the severe background present. We investigated a compact gamma-ray detector with a pinhole collimator and shielding housing. Experimental nuclear reactor measurements involved varying boron concentrations and artificial shifts of the sources. The system successfully resolved the 478 keV photopeak and detected 1 cm lateral displacements, confirming its suitability for precise boron dose monitoring.

Keywords: Artificial neural networks; BNCT; Gamma-ray detector.