The bright Easter bunny sign: a useful aide-memoire on MRI for costotransverse joint inflammation in axial spondyloarthritis

Clin Radiol. 2024 May;79(5):e744-e749. doi: 10.1016/j.crad.2024.01.034. Epub 2024 Feb 12.

Abstract

Aim: To assess the significance of the "bright Easter bunny" sign on magnetic resonance imaging (MRI) to indicate inflammatory costotransverse joint (CtJ) lesions to diagnose axial spondyloarthritis (ax-SpA).

Materials and methods: Consecutive cases of patients with ax-SpA from a specialist rheumatology clinic were analysed retrospectively over two cohorts, between 2012-2014 and 2018-2020, to determine newly diagnosed patients under the Assessment of SpondyloArthritis international Society (ASAS) criteria. Biological naive adult patients who underwent spine MRI and sacroiliac imaging with full immunological work-up and a C-reactive protein reading within 3 months of the scan were included. Blinded images were reviewed by experienced musculoskeletal radiologists.

Result: From the 1,284 cases that were identified, 40 cases met the inclusion criteria for this study. Seven out of the 40 cases (17.5%) identified inflammatory lesions at the CtJ with five (70%) showing concordance with the bright Easter bunny sign.

Conclusion: The bright Easter bunny sign is concordant with inflammatory costotransverse enthesitis. This aide-memoire radiological sign is often on overlooked edge-of-field sections and this emphasises the need to ensure adequate coverage of the CtJ on spine MRI protocols as an important anatomical site of inflammatory change in ax-SpA assessment.

MeSH terms

  • Adult
  • Axial Spondyloarthritis*
  • Humans
  • Inflammation / diagnostic imaging
  • Magnetic Resonance Imaging / methods
  • Retrospective Studies
  • Sacroiliac Joint / diagnostic imaging
  • Sacroiliac Joint / pathology
  • Sacroiliitis*
  • Spondylarthritis* / diagnostic imaging