Abstract
The presence of serotonin, substance P and enteroglucagon was investigated in 8 argentaffin and argyrophil midgut carcinoid tumours. All tumours were argentaffin and displayed formalin-induced fluorescence indicating a content of serotonin. In addition, all 8 tumours showed substance P immunoreactivity and 7 of them enteroglucagon immunoreactivity. The results indicate that the midgut carcinoid tumours are as a rule multihormonal.
MeSH terms
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Aged
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Carcinoid Tumor / metabolism
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Carcinoid Tumor / pathology*
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Female
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Fluorescent Antibody Technique
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Formaldehyde
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Gastrointestinal Hormones / metabolism*
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Glucagon-Like Peptides / metabolism*
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Humans
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Immunoenzyme Techniques
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Intestinal Neoplasms / metabolism
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Intestinal Neoplasms / pathology*
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Male
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Middle Aged
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Serotonin / metabolism*
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Substance P / metabolism*
Substances
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Gastrointestinal Hormones
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Formaldehyde
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Serotonin
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Substance P
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Glucagon-Like Peptides