[18F]DPA-714-PET-MRI reveals pronounced innate immunity in human anti-LGI1 and anti-CASPR2 limbic encephalitis

J Neurol. 2024 Jun;271(6):3653-3659. doi: 10.1007/s00415-024-12302-7. Epub 2024 Mar 12.
No abstract available

Publication types

  • Letter
  • Case Reports

MeSH terms

  • Autoantibodies* / immunology
  • Female
  • Humans
  • Immunity, Innate* / immunology
  • Intracellular Signaling Peptides and Proteins* / immunology
  • Limbic Encephalitis* / diagnostic imaging
  • Limbic Encephalitis* / immunology
  • Magnetic Resonance Imaging*
  • Male
  • Membrane Proteins* / immunology
  • Middle Aged
  • Nerve Tissue Proteins* / immunology
  • Positron-Emission Tomography*
  • Pyrazoles* / pharmacology
  • Pyrimidines

Substances

  • Pyrazoles
  • LGI1 protein, human
  • Intracellular Signaling Peptides and Proteins
  • Nerve Tissue Proteins
  • Autoantibodies
  • Membrane Proteins
  • CNTNAP2 protein, human
  • N,N-diethyl-2-(2-(4-(2-fluoroethoxy)phenyl)-5,7-dimethylpyrazolo(1,5-a)pyrimidin-3-yl)acetamide
  • Pyrimidines