Titin-Based Force Modulates Cardiac Thick and Thin Filaments

Circ Res. 2024 Apr 12;134(8):1026-1028. doi: 10.1161/CIRCRESAHA.123.323988. Epub 2024 Mar 14.

Authors

Anthony L Hessel¹, Michel N Kuehn¹, Nichlas M Engels², Devin L Nissen³, Johanna K Freundt¹, Weikang Ma³, Thomas C Irving³, Wolfgang A Linke¹

Affiliations

¹ Institute of Physiology II, University of Münster, Germany (A.L.H., M.N.K., J.K.F., W.A.L.).
² Department of Cellular and Molecular Medicine, The University of Arizona, Tucson (N.M.E.).
³ Biophysics Collaborative Access Team (BioCAT), Department of Biology, Illinois Institute of Technology, Chicago (D.L.N., W.M., T.C.I.).

PMID: 38482667
PMCID: PMC11046451 (available on 2025-04-12)
DOI: 10.1161/CIRCRESAHA.123.323988

No abstract available

Keywords: calcium; connectin; myocardium; myofibrils; sarcomeres.

Publication types

Letter

MeSH terms

Actin Cytoskeleton
Connectin / genetics
Heart*
Myofibrils
Sarcomeres*

Substances

Connectin

Grants and funding