Metformin induces a Lac-Phe gut-brain signalling axis

Nat Metab. 2024 Apr;6(4):603-605. doi: 10.1038/s42255-024-01014-x.

Author

Tara TeSlaa^{1

2

3}

Affiliations

¹ Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, CA, USA. [email protected].
² Molecular Biology Institute, University of California Los Angeles, Los Angeles, CA, USA. [email protected].
³ Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, CA, USA. [email protected].

PMID: 38499764
DOI: 10.1038/s42255-024-01014-x

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Letter

MeSH terms

Animals
Brain / drug effects
Brain / metabolism
Brain-Gut Axis*
Gastrointestinal Microbiome / drug effects
Humans
Hypoglycemic Agents / pharmacology
Metformin* / pharmacology
Phenylalanine*
Signal Transduction* / drug effects

Substances

Metformin
Hypoglycemic Agents
N-lactoyl-phenylalanine
Phenylalanine