Hypercompact TnpB and truncated TnpB systems enable efficient genome editing in vitro and in vivo

Cell Discov. 2024 Mar 19;10(1):31. doi: 10.1038/s41421-023-00645-w.

Ming Wang^#^{1

2}, Zhaolin Sun^#³, Yue Liu¹, Pengbin Yin⁴, Chuanyu Liang¹, Lin Tan¹, Lei Wei¹, Yuzhan Wang¹, Haikuan Yu⁴, Yunfei Zhu¹, Xiaoxiang Hu¹, Ning Li⁵, Ran Zhang^{6

7}

¹ State Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, China Agricultural University, Beijing, China.
² SciFriend Biotechnology Co., Ltd, Beijing, China.
³ Beijing Capital Agribusiness Future Biotechnology Co., Ltd, Beijing, China.
⁴ Department of Orthopaedics, Chinese PLA General Hospital, Beijing, China.
⁵ Beijing Capital Agribusiness Future Biotechnology Co., Ltd, Beijing, China. [email protected].
⁶ State Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, China Agricultural University, Beijing, China. [email protected].
⁷ Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, China. [email protected].

^# Contributed equally.

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