Determinants of Impaired Peak Oxygen Uptake in Breast Cancer Survivors: JACC: CardioOncology Primer

Stephen J Foulkes; Mark J Haykowsky; Todd Li; Jing Wang; Megan Kennedy; Amy A Kirkham; Richard B Thompson; D Ian Paterson; Andre La Gerche; Edith Pituskin

doi:10.1016/j.jaccao.2023.11.005

Determinants of Impaired Peak Oxygen Uptake in Breast Cancer Survivors: JACC: CardioOncology Primer

JACC CardioOncol. 2023 Dec 26;6(1):33-37. doi: 10.1016/j.jaccao.2023.11.005. eCollection 2024 Feb.

Authors

Stephen J Foulkes^{1

2}, Mark J Haykowsky¹, Todd Li¹, Jing Wang³, Megan Kennedy⁴, Amy A Kirkham⁵, Richard B Thompson¹, D Ian Paterson⁶, Andre La Gerche^{2

7}, Edith Pituskin¹

Affiliations

¹ College of Health Sciences, University of Alberta, Edmonton, Ontario, Canada.
² Heart, Exercise and Research Trials Lab, St Vincent's Institute of Medical Research, Melbourne, Victoria, Australia.
³ Division of Public Health, School of Medicine, University of Utah, Salt Lake City, Utah, USA.
⁴ University of Alberta Library, University of Alberta, Edmonton, Alberta, Canada.
⁵ Faculty of Kinesiology & Physical Education, University of Toronto, Toronto, Ontario, Canada.
⁶ Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
⁷ Cardiology Department, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.

Abstract

•Exercise intolerance is common among breast cancer survivors.•Exercise intolerance in breast cancer survivors is related to cardiac, vascular, and skeletal muscle impairments.•Holistic rehabilitation or pharmacological therapies are needed to address these impairments.

Keywords: breast cancer; exercise; oxygen consumption.

Publication types

Review