Systemic diffuse large B-cell lymphoma involving the central nervous system has high rates of defective antigen presentation and immune surveillance

Joel Wight; Piers Blombery; Jennifer Lickiss; Melinda Burgess; Clare Gould; Adrian Minson; Fiona Swain; Muhammed B Sabdia; Maher K Gandhi; Andrew Birchley; Colm Keane; Eliza A Hawkes

doi:10.3324/haematol.2023.284600

Systemic diffuse large B-cell lymphoma involving the central nervous system has high rates of defective antigen presentation and immune surveillance

Haematologica. 2024 Sep 1;109(9):3013-3018. doi: 10.3324/haematol.2023.284600.

Authors

Affiliations

¹ Austin Health, Heidelberg, Australia; Olivia Newton John Cancer Research Institute, Victoria, Australia; The University of Melbourne, Melbourne, Australia; Townsville University Hospital, Townsville. [email protected].
² Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia. 7. Princess Alexandra Hospital, Brisbane.
³ Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Victoria.
⁴ Princess Alexandra Hospital, Brisbane.
⁵ Mater Research Institute, The University of Queensland, Brisbane.
⁶ Princess Alexandra Hospital, Brisbane, Australia; Mater Research Institute, The University of Queensland, Brisbane, Australia; University of Queensland, Brisbane.
⁷ Townsville University Hospital, Townsville.
⁸ Princess Alexandra Hospital, Brisbane, Australia; University of Queensland, Brisbane.
⁹ Austin Health, Heidelberg, Australia; Olivia Newton John Cancer Research Institute, Victoria, Australia; The University of Melbourne, Melbourne, Australia; La Trobe University, Melbourne.

No abstract available

Publication types

Letter

MeSH terms

Adult
Aged
Antigen Presentation*
Central Nervous System Neoplasms* / diagnosis
Central Nervous System Neoplasms* / immunology
Central Nervous System Neoplasms* / pathology
Female
Humans
Immunologic Surveillance*
Lymphoma, Large B-Cell, Diffuse* / diagnosis
Lymphoma, Large B-Cell, Diffuse* / immunology
Lymphoma, Large B-Cell, Diffuse* / pathology
Male
Middle Aged

Grants and funding

Funding: The authors thank the Christine and Bruce Wilson Centre for Lymphoma Genomics for research funding. Seed funding was also provided by the Austin Health medical research fund.