Topical BCl-2 inhibitor (ABT-737) attenuates skin photoaging in mice

Exp Dermatol. 2024 Mar;33(3):e15051. doi: 10.1111/exd.15051.

Bingyi Yang¹, Jiao Jiang^{1

2

3}, Haijing Wu¹, Qianjin Lu^{1

2

3}

¹ Department of Dermatology, The Second Xiangya Hospital of Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, China.
² Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, Jiangsu, China.
³ Key Laboratory of Basic and Translational Research on Immune-Mediated Skin Diseases, Chinese Academy of Medical Sciences, Nanjing, Jiangsu, China.

No abstract available

Keywords: ABT‐737; BCL‐2 inhibitor; photoaging; senescence‐associated secretory phenotype; topical application.

MeSH terms