Identification of the novel null allele HLA-DPB1*1449:01N by next-generation sequencing

HLA. 2024 Mar;103(3):e15449. doi: 10.1111/tan.15449.

Abstract

The novel HLA-DPB1*1449:01N allele differs from HLA-DPB1*16:01:01:01 by a nucleotide at codon 92 in exon 2.

Keywords: HLA new allele; HLA‐DPB1; null allele; stop codon.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Exons / genetics
  • HLA-DP beta-Chains / genetics
  • High-Throughput Nucleotide Sequencing*
  • Humans

Substances

  • HLA-DPB1 antigen
  • HLA-DP beta-Chains