Transarterial Embolization of Renal Arteriovenous Malformations: Treatment Outcomes According to Angiographic Classification

J Vasc Interv Radiol. 2024 Jul;35(7):979-988.e1. doi: 10.1016/j.jvir.2024.03.024. Epub 2024 Mar 25.

Abstract

Purpose: To assess the different adjunctive catheter techniques required to achieve complete occlusion of renal arteriovenous malformations (rAVMs) of different angioarchitectural types.

Materials and methods: Overall, data on 18 patients with rAVM (Type 1, n = 7; Type 2, n = 2; Type 3, n = 9; mean age, 53.8 years) who underwent 25 procedures between 2011 and 2022 were reviewed. The clinical presentations, endovascular techniques, arteriovenous malformation (AVM) occlusion rate, adverse events (including the incidence of renal infarction), and clinical symptoms and outcomes (including recurrence/increase of AVM) were analyzed according to the Cho-Do angioarchitectural classification. Posttreatment renal infarction was classified as no infarction, small infarction (<12.5%), medium infarction (12.5%-25%), and large infarction (>25%) using contrast-enhanced computed tomography or magnetic resonance imaging.

Results: Hematuria and heart failure were presenting symptoms in 10 and 2 patients, respectively. The embolic materials used were as follows: Type 1 rAVM, coils alone or with n-butyl-2-cyanoacrylate (nBCA); Type 2 rAVM, nBCA alone or with coils; and Type 3 rAVMs, nBCA alone. Fourteen patients underwent adjunctive catheter techniques, including flow control with a balloon catheter and multiple microcatheter placement, alone or in combination. Immediate postprocedural angiography revealed complete occlusion in 15 patients (83%) and marked regression of rAVM in 3 (17%). Small asymptomatic renal infarctions were observed in 6 patients with Type 3 rAVMs without any decrease in renal function. No major adverse events were observed. All symptomatic patients experienced symptom resolution. Recurrence/increase of rAVM was not observed during the mean 32-month follow-up period (range, 2-120 months).

Conclusions: Transarterial embolization using adjunctive catheter techniques according to angioarchitectural types can be an effective treatment for rAVMs.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Arteriovenous Malformations* / diagnostic imaging
  • Arteriovenous Malformations* / therapy
  • Computed Tomography Angiography
  • Embolization, Therapeutic* / adverse effects
  • Enbucrilate / administration & dosage
  • Female
  • Humans
  • Infarction / diagnostic imaging
  • Infarction / etiology
  • Infarction / therapy
  • Magnetic Resonance Angiography
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Recurrence
  • Renal Artery* / abnormalities
  • Renal Artery* / diagnostic imaging
  • Renal Veins* / abnormalities
  • Renal Veins* / diagnostic imaging
  • Retrospective Studies
  • Risk Factors
  • Time Factors
  • Treatment Outcome
  • Young Adult

Substances

  • Enbucrilate