Applications of emerging extracellular vesicles technologies in the treatment of inflammatory diseases

Front Immunol. 2024 Mar 13:15:1364401. doi: 10.3389/fimmu.2024.1364401. eCollection 2024.

Abstract

The emerging extracellular vesicles technologies is an advanced therapeutic approach showing promising potential for addressing inflammatory diseases. These techniques have been proven to have positive effects on immune modulation and anti-inflammatory responses. With these advancements, a comprehensive review and update on the role of extracellular vesicles in inflammatory diseases have become timely. This review aims to summarize the research progress of extracellular vesicle technologies such as plant-derived extracellular vesicles, milk-derived extracellular vesicles, mesenchymal stem cell-derived extracellular vesicles, macrophage-derived extracellular vesicles, etc., in the treatment of inflammatory diseases. It elucidates their potential significance in regulating inflammation, promoting tissue repair, and treating diseases. The goal is to provide insights for future research in this field, fostering the application and development of extracellular vesicle technology in the treatment of inflammatory diseases.

Keywords: MSC-derived EVs; extracellular vesicles; inflammatory; macrophage-derived EVs; milk-derived EVs; plant-derived EVs.

Publication types

  • Review

MeSH terms

  • Extracellular Vesicles* / physiology
  • Humans
  • Inflammation / therapy
  • Mesenchymal Stem Cells* / physiology

Grants and funding

The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.