Propolis in the management of cardiovascular disease

Int J Biol Macromol. 2024 May;266(Pt 2):131219. doi: 10.1016/j.ijbiomac.2024.131219. Epub 2024 Mar 30.

Abstract

Background: Propolis is a resinous compound that is obtained from honey bees. It consists of numerous chemical constituents that impart different therapeutic action. The heart is the core of the body and cardiovascular disease (CVD) is a burden for the human being. This article emphasizes how propolis is fruitful in the management of various CVDs.

Scope and approach: This review focuses on how various constituents of the propolis (such as terpenes, flavonoids, phenolics, etc.) impart cardio protective actions.

Key finding and conclusion: With the support of various clinical trials and research outcomes, it was concluded that propolis owns niche cardio protective properties that can be a boon for various cardiac problems (both in preventive and therapeutic action) such as atherosclerosis, excessive angiogenesis, hypertension, and many more.

Keywords: Angiogenesis; Atherosclerosis; Heart failure; Inflammation; Propolis.

Publication types

  • Review

MeSH terms

  • Animals
  • Cardiovascular Diseases* / drug therapy
  • Flavonoids / chemistry
  • Flavonoids / pharmacology
  • Flavonoids / therapeutic use
  • Humans
  • Propolis* / chemistry
  • Propolis* / therapeutic use

Substances

  • Flavonoids
  • Propolis