Clinical genetics in breast cancer

J Surg Oncol. 2024 Jul;130(1):16-22. doi: 10.1002/jso.27630. Epub 2024 Apr 1.

Abstract

As genetic testing becomes increasingly more accessible and more applicable with a broader range of clinical implications, it may also become more challenging for breast cancer providers to remain up-to-date. This review outlines some of the current clinical guidelines and recent literature surrounding germline genetic testing, as well as genomic testing, in the screening, prevention, diagnosis, and treatment of breast cancer, while identifying potential areas of further research.

Keywords: breast cancer; genetic testing; genomic testing; hereditary; patient outcomes.

Publication types

  • Review

MeSH terms

  • Breast Neoplasms* / genetics
  • Breast Neoplasms* / pathology
  • Breast Neoplasms* / therapy
  • Female
  • Genetic Predisposition to Disease
  • Genetic Testing*
  • Germ-Line Mutation
  • Humans