Anaplastic Large Cell Lymphoma (ALCL) With a Sarcomatoid Variant Presenting As Distributive Shock in a 41-Year-Old Female: A Case Report

Cureus. 2024 Feb 29;16(2):e55235. doi: 10.7759/cureus.55235. eCollection 2024 Feb.

Abstract

The sarcomatoid variant is considered a rare subtype of anaplastic large cell lymphoma. We present a 40-year-old diabetic female who was evaluated in the ER for distributive shock, requiring vasopressors and mechanical ventilation. An extensive workup was negative for infection. A serial CT scan of the abdomen and pelvis showed evolving lymphadenopathy, and a biopsy revealed malignant anaplastic lymphoma cells with a sarcomatous variant. The oncology team recommended the initiation of inpatient chemotherapy; however, the family opted to proceed with comfort care measures.

Keywords: alk-positive; anaplastic large cell lymphoma (alcl); anaplastic lymphoma kinase; distributive shock; sarcomatoid variant.

Publication types

  • Case Reports