A case report on rapid development of simultaneous liver and musculature calcifications in severe sepsis

Clin Med (Lond). 2024 Mar;24(2):100036. doi: 10.1016/j.clinme.2024.100036. Epub 2024 Apr 6.

Abstract

A 76-year-old Malay female presented with 2 days history of fever and vomiting. She was found to have Escherichia coli and Klebsiella pneumoniae bacteraemia with no clear intra-abdominal cause on the initial computed tomography of the abdomen and pelvis (CTAP). She clinically improved with 2 weeks duration of intravenous meropenem. She subsequently developed septic shock and a repeated CTAP demonstrated increased hepatic parenchymal density with extensive parenchymal calcifications. Curvilinear calcifications were seen in the paraspinal and pelvic musculature.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Calcinosis* / diagnostic imaging
  • Escherichia coli Infections / complications
  • Escherichia coli Infections / diagnosis
  • Escherichia coli Infections / drug therapy
  • Female
  • Humans
  • Klebsiella Infections / complications
  • Klebsiella Infections / diagnosis
  • Klebsiella Infections / drug therapy
  • Klebsiella pneumoniae / isolation & purification
  • Liver Diseases / diagnostic imaging
  • Meropenem / administration & dosage
  • Meropenem / therapeutic use
  • Muscular Diseases / diagnostic imaging
  • Sepsis / microbiology
  • Tomography, X-Ray Computed

Substances

  • Anti-Bacterial Agents
  • Meropenem