Transoral robotic surgery with free flap reconstruction: Functional outcomes of 241 patients at a single institution

Head Neck. 2024 Jul;46(7):1601-1613. doi: 10.1002/hed.27761. Epub 2024 Apr 10.

Abstract

Background: Transoral robotic surgery (TORS) for oropharyngeal malignancy optimizes oncologic outcomes while preserving functionality. This study identifies patterns of functional recovery after TORS with free flap reconstruction (FFR).

Methods: Retrospective cohort study at a tertiary care center of patients with primary oropharyngeal tumors treated with TORS with FFR between 2010 and 2022. Patients were categorized into: adjuvant chemoradiation or radiation, or no adjuvant therapy (NAT). Functional outcomes were measured by functional oral intake scale (FOIS).

Results: 241 patients were included. FOIS declined at first postoperative appointment (median = 7.0 to 2.0, IQR = [7.0, 7.0], [2.0, 4.0]), and progressively improved to 6.0 (5.0, 6.0) after 1 year, with NAT having the highest FOIS (7.0, p < 0.05). Predictors of poor long-term FOIS included RT and hypoglossal nerve (CN XII) involvement (p < 0.05).

Conclusions: TORS with FFR leads to good long-term function with minimal intake restrictions. Radiation therapy and CN XII involvement increase risk of worse functional outcomes.

Keywords: FOIS; TORS; dysphagia; free flap; functional outcomes.

MeSH terms

  • Adult
  • Aged
  • Cohort Studies
  • Female
  • Free Tissue Flaps*
  • Humans
  • Male
  • Middle Aged
  • Oropharyngeal Neoplasms* / pathology
  • Oropharyngeal Neoplasms* / surgery
  • Plastic Surgery Procedures* / methods
  • Recovery of Function
  • Retrospective Studies
  • Robotic Surgical Procedures*
  • Treatment Outcome