Efficacy of dupilumab as an alternative to corticosteroids in the treatment of exacerbations of allergic bronchopulmonary aspergillosis

Masamitsu Hamakawa; Tadashi Ishida

doi:10.1002/rcr2.1354

Efficacy of dupilumab as an alternative to corticosteroids in the treatment of exacerbations of allergic bronchopulmonary aspergillosis

Respirol Case Rep. 2024 Apr 11;12(4):e01354. doi: 10.1002/rcr2.1354. eCollection 2024 Apr.

Authors

Masamitsu Hamakawa¹, Tadashi Ishida¹

Affiliation

¹ Department of Respiratory Medicine Kurashiki Central Hospital Okayama Japan.

Abstract

The pathogenesis of allergic bronchopulmonary aspergillosis involves not only eosinophils but also plasma cells that produce immunoglobulin E. Dupilumab may be an effective alternative to corticosteroids because it inhibits T cell to plasma cell differentiation by blocking IL4.

Keywords: ABPA; allergic bronchopulmonary aspergillosis; asthma; dupilumab.

Publication types

Case Reports