Case of pediatric cerebellar, hippocampal, and basal nuclei transient edema with restricted diffusion (CHANTER) syndrome in a 2-year-old girl

Pediatr Radiol. 2024 Jun;54(7):1220-1223. doi: 10.1007/s00247-024-05928-2. Epub 2024 Apr 17.

Abstract

Cerebellar, hippocampal, and basal nuclei transient edema with restricted diffusion (CHANTER) syndrome is a recently described entity that refers to a specific pattern of cerebellar edema with restricted diffusion and crowding of the fourth ventricle among other findings. The syndrome is commonly associated with toxic opioid exposure. While most commonly seen in adults, we present a case of a 2-year-old girl who survived characteristic history and imaging findings of CHANTER syndrome.

Keywords: CHANTER; Cerebellar infarction; Child; Opioid.

Publication types

  • Case Reports

MeSH terms

  • Brain Edema* / diagnostic imaging
  • Cerebellar Diseases / complications
  • Cerebellar Diseases / diagnostic imaging
  • Cerebellum / diagnostic imaging
  • Cerebellum / pathology
  • Child, Preschool
  • Diagnosis, Differential
  • Diffusion Magnetic Resonance Imaging / methods
  • Female
  • Hippocampus* / diagnostic imaging
  • Hippocampus* / pathology
  • Humans
  • Magnetic Resonance Imaging / methods
  • Syndrome