Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation

Cell Res. 2024 Jul;34(7):522-525. doi: 10.1038/s41422-024-00962-z. Epub 2024 Apr 19.

Authors

Xianwen Ye^#¹, Zixuan Huang^#¹, Yi Li¹, Mengjiao Wang¹, Wanyu Meng¹, Maojian Miao¹, Jingdong Cheng²

Affiliations

¹ Minhang Hospital & Institutes of Biomedical Sciences, Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism, Fudan University, Shanghai, China.
² Minhang Hospital & Institutes of Biomedical Sciences, Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism, Fudan University, Shanghai, China. [email protected].

^# Contributed equally.

No abstract available

Publication types

Letter

MeSH terms

Apoptosis Regulatory Proteins* / genetics
Apoptosis Regulatory Proteins* / metabolism
Humans
Protein Binding
Protein Biosynthesis*
RNA, Messenger / genetics
RNA, Messenger / metabolism
RNA-Binding Proteins* / genetics
RNA-Binding Proteins* / metabolism
Ribosomes* / metabolism

Substances

RNA-Binding Proteins
PDCD4 protein, human
Apoptosis Regulatory Proteins
RNA, Messenger

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