Optimizing lipid control in Taiwanese diabetic patients: A collaborative consensus by the Diabetes Association of the Republic of China (Taiwan) and the Taiwanese Association of Diabetes Educators

Feng-Chih Shen; Chih-Hsun Chu; Jung-Fu Chen; Chin-Sung Kuo; Chih-Yao Hsu; Ching-Han Lin; Yi-Jing Sheen; Sheng-Chiang Su; Kai-Jen Tien; Chieh-Hua Lu; Chun-Chuan Lee; Yi-Sun Yang; Shih-Te Tu; Po-Tsang Chen; Ching-Chu Chen; Ming-Nan Chien; Hung-Yuan Li; Wayne Huey-Herng Sheu; Chien-Ning Huang; Chih-Yuan Wang; Horng-Yih Ou

doi:10.1111/jdi.14222

Optimizing lipid control in Taiwanese diabetic patients: A collaborative consensus by the Diabetes Association of the Republic of China (Taiwan) and the Taiwanese Association of Diabetes Educators

J Diabetes Investig. 2024 Aug;15(8):1151-1160. doi: 10.1111/jdi.14222. Epub 2024 Apr 27.

Authors

Feng-Chih Shen^{1

2}, Chih-Hsun Chu³, Jung-Fu Chen^{1

2}, Chin-Sung Kuo^{4

5}, Chih-Yao Hsu⁶, Ching-Han Lin⁷, Yi-Jing Sheen^{8

9

10}, Sheng-Chiang Su¹¹, Kai-Jen Tien¹², Chieh-Hua Lu¹¹, Chun-Chuan Lee^{13

14}, Yi-Sun Yang^{15

16}, Shih-Te Tu¹⁷, Po-Tsang Chen¹⁸, Ching-Chu Chen^{19

20}, Ming-Nan Chien^{13

14}, Hung-Yuan Li²¹, Wayne Huey-Herng Sheu^{9

22}, Chien-Ning Huang^#^{15

16}, Chih-Yuan Wang^#^{21

23}, Horng-Yih Ou^#⁷

Affiliations

¹ Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
² School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
³ Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
⁴ Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
⁵ Division of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
⁶ Department of Internal Medicine, Taipei City Hospital, Ren-Ai Branch, Taipei, Taiwan.
⁷ Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
⁸ Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung City, Taiwan.
⁹ School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
¹⁰ Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan.
¹¹ Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
¹² Renxin Clinics, Tainan, Taiwan.
¹³ Division of Endocrinology and Metabolism, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, Taiwan.
¹⁴ Department of Medicine, MacKay Medical College, New Taipei City, Taiwan.
¹⁵ Division of Endocrinology and Metabolism, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.
¹⁶ School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
¹⁷ Division of Endocrinology and Metabolism, Department of Medicine, Changhua Christian Hospital, Changhua, Taiwan.
¹⁸ Yong De-Kang Internal Medicine Clinic, Tainan, Taiwan.
¹⁹ Division of Endocrinology and Metabolism, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.
²⁰ School of Chinese Medicine, China Medical University, Taichung, Taiwan.
²¹ Division of Endocrinology and Metabolism, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
²² Institute of Molecular and Genetic Medicine, National Health Research Institutes, Miaoli, Taiwan.
²³ Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.

^# Contributed equally.

Abstract

We present an in-depth analysis of dyslipidemia management strategies for patients with diabetes mellitus in Taiwan. It critically examines the disparity between established guideline recommendations and actual clinical practices, particularly in the context of evolving policies affecting statin prescriptions. The focus is on synthesizing the most recent findings concerning lipid management in patients with diabetes mellitus, with a special emphasis on establishing consensus regarding low-density lipoprotein cholesterol treatment targets. The article culminates in providing comprehensive, evidence-based recommendations tailored to the unique needs of those living with diabetes mellitus in Taiwan. It underscores the criticality of personalized care approaches, which incorporate multifaceted factors, and the integration of novel therapeutic options to enhance cardiovascular health outcomes.

Keywords: Diabetes; Hyperlipidemia; Statin.

MeSH terms

Cholesterol, LDL / blood
Consensus*
Diabetes Mellitus / therapy
Dyslipidemias* / drug therapy
Dyslipidemias* / therapy
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use
Practice Guidelines as Topic / standards
Taiwan / epidemiology

Substances

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Cholesterol, LDL