Greater mesophyll conductance and leaf photosynthesis in the field through modified cell wall porosity and thickness via AtCGR3 expression in tobacco

Plant Biotechnol J. 2024 Sep;22(9):2504-2517. doi: 10.1111/pbi.14364. Epub 2024 Apr 30.

Abstract

Mesophyll conductance (gm) describes the ease with which CO2 passes from the sub-stomatal cavities of the leaf to the primary carboxylase of photosynthesis, Rubisco. Increasing gm is suggested as a means to engineer increases in photosynthesis by increasing [CO2] at Rubisco, inhibiting oxygenation and accelerating carboxylation. Here, tobacco was transgenically up-regulated with Arabidopsis Cotton Golgi-related 3 (CGR3), a gene controlling methylesterification of pectin, as a strategy to increase CO2 diffusion across the cell wall and thereby increase gm. Across three independent events in tobacco strongly expressing AtCGR3, mesophyll cell wall thickness was decreased by 7%-13%, wall porosity increased by 75% and gm measured by carbon isotope discrimination increased by 28%. Importantly, field-grown plants showed an average 8% increase in leaf photosynthetic CO2 uptake. Up-regulating CGR3 provides a new strategy for increasing gm in dicotyledonous crops, leading to higher CO2 assimilation and a potential means to sustainable crop yield improvement.

Keywords: AtCGR3 pectin methyltransferase; CO2 assimilation; carbon isotope discrimination; mesophyll conductance; photosynthetic efficiency; water use efficiency.

MeSH terms

  • Arabidopsis / genetics
  • Arabidopsis / metabolism
  • Arabidopsis / physiology
  • Arabidopsis Proteins / genetics
  • Arabidopsis Proteins / metabolism
  • Carbon Dioxide* / metabolism
  • Cell Wall* / metabolism
  • Gene Expression Regulation, Plant
  • Mesophyll Cells* / metabolism
  • Nicotiana* / cytology
  • Nicotiana* / genetics
  • Nicotiana* / metabolism
  • Nicotiana* / physiology
  • Photosynthesis*
  • Plant Leaves / genetics
  • Plant Leaves / metabolism
  • Plant Leaves / physiology
  • Plants, Genetically Modified
  • Porosity

Substances

  • Arabidopsis Proteins
  • Carbon Dioxide