Transient albuminuria in the setting of short-term severe hyperglycemia in type 1 diabetes

J Diabetes Complications. 2024 Jun;38(6):108762. doi: 10.1016/j.jdiacomp.2024.108762. Epub 2024 Apr 29.

Abstract

In a cohort of 1817 children with type 1 diabetes (T1D), short-term hyperglycemia was associated with transient albuminuria (11 % during new-onset T1D without diabetic ketoacidosis (DKA), 12 % during/after DKA, 6 % during routine screening). Our findings have implications regarding future risk of diabetic kidney disease and further investigation is needed.

Keywords: Diabetic ketoacidosis; Type 1 diabetes; Urine albumin-to-creatinine ratio.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Albuminuria*
  • Child
  • Child, Preschool
  • Cohort Studies
  • Diabetes Mellitus, Type 1* / complications
  • Diabetic Ketoacidosis / complications
  • Diabetic Nephropathies* / complications
  • Diabetic Nephropathies* / diagnosis
  • Diabetic Nephropathies* / epidemiology
  • Female
  • Humans
  • Hyperglycemia* / complications
  • Male
  • Severity of Illness Index