Melatonin use in managing insomnia in children with autism and other neurogenetic disorders - An assessment by the international pediatric sleep association (IPSA)

Sleep Med. 2024 Jul:119:222-228. doi: 10.1016/j.sleep.2024.04.008. Epub 2024 Apr 20.

Abstract

Though it is widely prescribed for improving sleep of children with autism and other neurogenetic disorders, there is a need for practical guidance to clinicians on the use of melatonin for managing insomnia in this population. Because data were either lacking or inconclusive, a task force was established by the International Pediatric Sleep Association (IPSA) to examine the literature based on clinical trials from 2012 onwards. A summary of evidence pertaining to melatonin's utility and potential side effects, practice-related caveats, and insights for use are published herewith.

MeSH terms

  • Autistic Disorder / complications
  • Autistic Disorder / drug therapy
  • Child
  • Humans
  • Melatonin* / therapeutic use
  • Sleep Initiation and Maintenance Disorders* / drug therapy

Substances

  • Melatonin