Vesicoureteral reflux postoperative radical nephroureterectomy for upper urinary tract urothelial carcinoma: A case report

Mueataz A Mahyoub; Bassam Musleh Yousef; Radman A M Ghaleb; Saleh Obad; Abdullatif Mothanna; Fayed Al-Yousofy; Mohamed Elhoumed; Mustafa Abbas; Mohammed Alnaggar; Mudan Ren; Shuixiang He

doi:10.1016/j.heliyon.2024.e30294

Vesicoureteral reflux postoperative radical nephroureterectomy for upper urinary tract urothelial carcinoma: A case report

Heliyon. 2024 Apr 26;10(9):e30294. doi: 10.1016/j.heliyon.2024.e30294. eCollection 2024 May 15.

Authors

Mueataz A Mahyoub^{1

2

3}, Bassam Musleh Yousef⁴, Radman A M Ghaleb⁵, Saleh Obad⁶, Abdullatif Mothanna⁷, Fayed Al-Yousofy⁸, Mohamed Elhoumed^{9

10}, Mustafa Abbas³, Mohammed Alnaggar^{11

12}, Mudan Ren^{1

2}, Shuixiang He^{1

2}

Affiliations

¹ Department of Gastroenterology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
² Clinical Medical Research Center for Digestive Diseases (Oncology) of Shaanxi Province, Xi'an, China.
³ Department of Internal Medicine, Faculty of Medicine, Thamar University, Thamar, Yemen.
⁴ Department of Urology, Al- Ameen Typical Hospital, Ibb, Yemen.
⁵ Department of Urology, Faculty of Medicine, Taiz University, Taiz, Yemen.
⁶ Department of Anesthesiology, Al- Ameen Typical Hospital, Ibb, Yemen.
⁷ Department of Radiology, Ibb Scan Center, Ibb, Yemen.
⁸ Department of Pathology, Faculty of Medicine, Taiz University, Taiz, Yemen.
⁹ Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China.
¹⁰ National Institute of Public Health Research (INRSP), BP. 695, Nouakchott, Mauritania.
¹¹ Department of Internal Medicine, Clinic Medical College, Hubei University of Science and Technology, Xianning, Hubei, China.
¹² Department of Oncology, South Hubei Cancer Hospital, Xianning, Hubei, China.

Abstract

Introduction: Primary Upper tract urothelial carcinoma (UTUC) is a rare subtype of urothelial carcinoma and has an unknown incidence and prevalence in Yemen. Radical nephroureterectomy (RNU) with bladder cuff removal is the standard treatment for UTUC.

Case presentation: We present a 67-year-old male patient who developed grade II vesicoureteral reflux (VUR) on the left side of the urinary tract after undergoing right-sided RNU for non-invasive UTUC. Follow-up examinations at one-, three-, and six-month post-surgery revealed no evidence of kidney diseases. The patient's recovery has been satisfactory, and ongoing regular follow-ups are being maintained.

Conclusion: Vigilant monitoring of VUR presence and effective management following RNU is crucial to minimize complications and preserve renal function. The underlying mechanisms linking VUR development and RNU remain unclear, necessitating further research.

Keywords: Ascending cystography; Radical nephroureterectomy; Upper urinary tract urothelial carcinoma; Vesicoureteral reflux.

Publication types

Case Reports