Silver-Catalyzed Carbofluorination of Olefins and α-Fluoroolefins with Carbamoyl Radicals

The reactivity of carbamoyl radicals, generated in situ from sodium oxamate salts, has been investigated in the context of radical carbofluorination reactions of olefins and α-fluoroolefins, respectively. Both transformations are catalyzed by silver salts and required the presence of potassium persulfate (K₂S₂O₈) and Selectfluor^TM as a radicophilic fluorine source. The reported methods provide a direct access to β-fluoroamides and β,β-difluoroamides.