Salmonella Hadar linked to two distinct transmission vehicles highlights challenges to enteric disease outbreak investigations

Epidemiol Infect. 2024 May 13:152:e86. doi: 10.1017/S0950268824000682.

Abstract

In 2020, an outbreak of Salmonella Hadar illnesses was linked to contact with non-commercial, privately owned (backyard) poultry including live chickens, turkeys, and ducks, resulting in 848 illnesses. From late 2020 to 2021, this Salmonella Hadar strain caused an outbreak that was linked to ground turkey consumption. Core genome multilocus sequence typing (cgMLST) analysis determined that the Salmonella Hadar isolates detected during the outbreak linked to backyard poultry and the outbreak linked to ground turkey were closely related genetically (within 0-16 alleles). Epidemiological and traceback investigations were unable to determine how Salmonella Hadar detected in backyard poultry and ground turkey were linked, despite this genetic relatedness. Enhanced molecular characterization methods, such as analysis of the pangenome of Salmonella isolates, might be necessary to understand the relationship between these two outbreaks. Similarly, enhanced data collection during outbreak investigations and further research could potentially aid in determining whether these transmission vehicles are truly linked by a common source and what reservoirs exist across the poultry industries that allow Salmonella Hadar to persist. Further work combining epidemiological data collection, more detailed traceback information, and genomic analysis tools will be important for monitoring and investigating future enteric disease outbreaks.

Keywords: Salmonella; outbreaks; public health; zoonotic foodborne diseases.

MeSH terms

  • Animals
  • Chickens / microbiology
  • Disease Outbreaks*
  • Ducks / microbiology
  • Humans
  • Multilocus Sequence Typing
  • Poultry / microbiology
  • Poultry Diseases* / epidemiology
  • Poultry Diseases* / microbiology
  • Poultry Diseases* / transmission
  • Salmonella Infections / epidemiology
  • Salmonella Infections / microbiology
  • Salmonella Infections / transmission
  • Salmonella Infections, Animal / epidemiology
  • Salmonella Infections, Animal / microbiology
  • Salmonella Infections, Animal / transmission
  • Salmonella* / classification
  • Salmonella* / genetics
  • Salmonella* / isolation & purification
  • Turkeys* / microbiology