The Impact of Time Since Menarche for Depressive and Anxiety Symptom Severity in Adolescence and Young Adulthood

J Adolesc Health. 2024 Aug;75(2):281-287. doi: 10.1016/j.jadohealth.2024.03.010. Epub 2024 May 12.

Abstract

Purpose: The study mapped depressive and anxiety symptom trajectories throughout adolescence and early adulthood, arrayed by time since menarche, a novel indicator of pubertal change and examined the effect of age of menarche and pubertal timing, more frequently used variables, on depressive and anxiety symptom severity trajectories.

Methods: Secondary analysis of a cross-sequential prospective longitudinal investigation included a community sample of 262 US, adolescent females. Participants were enrolled in age cohorts of 11, 13, 15, and 17 years. Four annual waves of data were collected. Self-report of age at menarche was categorized into pubertal timing categories. A novel measure "time since menarche" (chronological age at each wave minus age at menarche), was measured along with depressive and anxiety symptom severity. Two-piece growth curve modeling with landmark registration examined depressive and anxiety symptom severity trajectories according to time since menarche.

Results: There was no change (p > .05) in depression and anxiety symptom severity before menarche; however, in the years leading away from menarche, depression and anxiety symptom severity decreased (p < .05). Age at menarche was not associated with change in depressive and anxiety symptom severity (p > .05) and there were no moderating effects of pubertal timing.

Discussion: Depressive and anxiety symptoms decrease in the years leading away from menarche, suggesting puberty-related psychopathology may be transitory in some individuals. Time since menarche may be a clinically relevant indicator of psychological functioning in pubescent adolescent females. Future studies should examine this variable in larger samples, including more adolescents in the earlier stages of puberty.

Keywords: Adolescent; Anxiety; Depression; Puberty; Time since menarche.

MeSH terms

  • Adolescent
  • Age Factors
  • Anxiety* / psychology
  • Child
  • Depression* / psychology
  • Female
  • Humans
  • Longitudinal Studies
  • Menarche* / physiology
  • Menarche* / psychology
  • Prospective Studies
  • Puberty / physiology
  • Puberty / psychology
  • Severity of Illness Index
  • Time Factors
  • Young Adult