The association of bariatric surgery with myocardial infarction and coronary revascularization: a propensity score match analysis of National Inpatient Sample

Surg Obes Relat Dis. 2024 Sep;20(9):856-863. doi: 10.1016/j.soard.2024.04.010. Epub 2024 Apr 13.

Abstract

Background: Metabolic bariatric surgery (MBS) not only leads to a durable weight loss but also lowers mortality, and reduces cardiovascular risks.

Objectives: The current study aims to investigate the association of bariatric metabolic surgery (BMS) with admissions for acute myocardial infarction (AMI), including ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI), as well as, coronary revascularization procedures, including percutaneous coronary intervention (PCI), coronary artery bypass graft (CABG), and thrombolysis.

Setting: The National Inpatient Sample (NIS) database.

Methods: The NIS data from 2016 to 2020 were analyzed. A propensity score matching in a 1:1 ratio was performed to match patients with history of MBS with non-MBS group.

Results: Two hundred thirty-three thousand seven hundred twenty-nine patients from the non-MBS group were matched with 233,729 patients with history of MBS. The MBS group had about 52% reduced odds of admission for AMI compared to the non-MBS group (adjusted odd ratio: .477, 95% confidence interval: .454-.502, P value <.001). In addition, the odds of STEMI and NSEMI were significantly lower in the MBS group in comparison to the non-MBS group. Also, the MBS group had significantly lower odds of CABG, PCI, and thrombolysis compared to the non-MBS group. In addition, in patients with AMI, MBS was associated with lower in-hospital mortality (adjusted odd ratio: .627, 95% confidence interval: .469-.839, P value = .004), length of hospital stays, and total charges.

Conclusions: History of MBS is significantly associated with reduced risk of admission for AMI including STEMI and NSTEMI, as well as the, need for coronary revascularization such as PCI and CABG.

Keywords: Bariatric surgery; Cardiovascular disease; Coronary artery bypass graft; Diabetes; Myocardial infarction; Obesity; Percutaneous coronary intervention.

MeSH terms

  • Adult
  • Aged
  • Bariatric Surgery* / statistics & numerical data
  • Coronary Artery Bypass / statistics & numerical data
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction* / epidemiology
  • Myocardial Infarction* / surgery
  • Myocardial Revascularization / statistics & numerical data
  • Percutaneous Coronary Intervention / statistics & numerical data
  • Propensity Score*
  • Retrospective Studies
  • ST Elevation Myocardial Infarction / epidemiology
  • ST Elevation Myocardial Infarction / mortality
  • ST Elevation Myocardial Infarction / surgery
  • United States / epidemiology