1 Department of Ophthalmology (JMH, LYS, EDG), Massachusetts Eye and Ear Infirmary, Boston, Massachusetts; Harvard Medical School (JMH, LYS, ATG, ABF, AA-J, EDG), Boston, Massachusetts; Department of Ophthalmology (ABF), Boston Children's Hospital, Boston, Massachusetts; Department of Neurology (AA-J), Massachusetts General Hospital, Boston, Massachusetts; and Picower Institute for Learning and Memory (EDG), Massachusetts Institute of Technology, Cambridge, Massachusetts.