Glial plasticity in the zebrafish central nervous system

Clara Mutschler; Stephanie B Telerman

doi:10.1016/j.tcb.2024.04.006

Glial plasticity in the zebrafish central nervous system

Trends Cell Biol. 2024 Jul;34(7):531-534. doi: 10.1016/j.tcb.2024.04.006. Epub 2024 May 16.

Authors

Clara Mutschler¹, Stephanie B Telerman²

Affiliations

¹ John Van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0PY, UK; Department of Genetics, University of Cambridge, Downing Site, Cambridge CB2 3EH, UK.
² Department of Genetics, University of Cambridge, Downing Site, Cambridge CB2 3EH, UK. Electronic address: [email protected].

PMID: 38760196
DOI: 10.1016/j.tcb.2024.04.006

Abstract

Glial cells have a remarkable plasticity. Recent studies using zebrafish as a model highlight conserved cellular behavior in health and disease in the central nervous system (CNS) between zebrafish and humans. These findings inform our understanding of their function and how their dysregulation in pathogenesis can be determinant.

Keywords: CNS; cellular plasticity; glial cells; neurodegeneration; neuropathology; zebrafish.

Publication types

Review

MeSH terms

Animals
Cell Plasticity
Central Nervous System* / metabolism
Humans
Neuroglia* / metabolism
Neuronal Plasticity
Zebrafish*