REM sleep: Out-dreaming fear

Brittany J Dugan; Jimmy J Fraigne; John Peever

doi:10.1016/j.cub.2024.04.033

REM sleep: Out-dreaming fear

Curr Biol. 2024 May 20;34(10):R510-R512. doi: 10.1016/j.cub.2024.04.033.

Authors

Brittany J Dugan¹, Jimmy J Fraigne¹, John Peever²

Affiliations

¹ Department of Cell and Systems Biology, University of Toronto, Toronto ON, Canada.
² Department of Cell and Systems Biology, University of Toronto, Toronto ON, Canada. Electronic address: [email protected].

PMID: 38772341
DOI: 10.1016/j.cub.2024.04.033

Abstract

The ability to forget fear-inducing situations is essential for adapting to our environment, but the neural mechanisms underlying 'fear forgetting' remain unclear. Novel findings reveal that the activity of the infralimbic cortex - specifically during REM sleep - contributes to the extinction of fear memory.

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MeSH terms

Animals
Dreams / physiology
Dreams / psychology
Extinction, Psychological / physiology
Fear* / physiology
Humans
Memory* / physiology
Sleep, REM* / physiology