Effects of high-intensity interval robot-assisted gait training on cardiopulmonary function and walking ability in chronic stroke survivors: A multicenter single-blind randomized controlled trial

J Back Musculoskelet Rehabil. 2024;37(5):1309-1319. doi: 10.3233/BMR-230385.

Abstract

Background: Chronic stroke can impair cardiopulmonary function, mobility, and daily activities. This study assessed the impact of robot-assisted gait training (RAGT) on such impairments.

Objective: To investigate the effects of robot-assisted gait training on cardiopulmonary function, walking ability, lower extremity function and strength, activities of daily living (ADLs), and blood test results among individuals with chronic stroke.

Methods: A multicenter, prospective, single-blinded, randomized controlled trial with 22 chronic stroke participants compared RAGT against a control exercise regimen. RAGT involved three days weekly sessions of high-intensity interval training for 8 weeks (24 sessions) with a Morning Walk® device. The control group also performed home exercises. (24 sessions) Measures included VO2max, Functional Ambulatory Category, 2-minute walk test, 10-meter walk test, Motricity Index-Lower, Korean version of the Fugl-Meyer Assessment Scale, Modified Barthel Index, Berg Balance Scale, muscle strength, InBody body composition, and blood tests (cholesterol, lipid, glucose).

Results: RAGT significantly improved VO2max, gait, balance, and lower limb strength compared with controls, with significant improvements in 2-minute walk test, 10-meter walk test, Motricity Index-Lower, and Fugl-Meyer Assessment outcomes. No changes were seen in muscle mass or blood markers.

Conclusion: RAGT enhances cardiopulmonary function and ambulatory capacity in chronic stroke patients, underscoring its potential in stroke rehabilitation.

Keywords: Cerebrovascular accident; high-intensity interval training; rehabilitation; robotics.

Publication types

  • Randomized Controlled Trial
  • Multicenter Study

MeSH terms

  • Activities of Daily Living
  • Aged
  • Chronic Disease
  • Exercise Therapy / methods
  • Female
  • Gait / physiology
  • Gait Disorders, Neurologic / etiology
  • Gait Disorders, Neurologic / physiopathology
  • Gait Disorders, Neurologic / rehabilitation
  • High-Intensity Interval Training / methods
  • Humans
  • Male
  • Middle Aged
  • Muscle Strength / physiology
  • Oxygen Consumption / physiology
  • Prospective Studies
  • Robotics*
  • Single-Blind Method
  • Stroke / physiopathology
  • Stroke Rehabilitation* / methods
  • Walk Test
  • Walking* / physiology