[Topical immunomodulators for persistent high‑risk human papillomavirus infection: experts consensus in China]

Zhonghua Fu Chan Ke Za Zhi. 2024 May 25;59(5):337-342. doi: 10.3760/cma.j.cn112141-20231211-00252.
[Article in Chinese]

Abstract

高危型人乳头状瘤病毒(HR-HPV)持续感染是唯一明确的子宫颈癌致病因素,并且与子宫颈上皮内瘤变(CIN)的发生密切相关。外用免疫调节剂(如外用红色诺卡菌细胞壁骨架)的出现有望改变子宫颈HR-HPV持续感染的治疗现状。本共识专家组由全国27位妇科临床专家、病毒学专家及流行病学专家组成,基于国内外研究证据和专家经验,经讨论就外用免疫调节剂的临床应用达成共识,推荐用于子宫颈单纯性HR-HPV持续感染、低级别鳞状上皮内病变[LSIL(CINⅠ)]合并HR-HPV持续感染以及高级别鳞状上皮内病变[HSIL(CIN Ⅱ/Ⅲ)]术后合并HR-HPV持续感染。.

MeSH terms

  • Administration, Topical
  • China
  • Consensus*
  • Female
  • Humans
  • Immunologic Factors* / administration & dosage
  • Immunologic Factors* / therapeutic use
  • Papillomaviridae
  • Papillomavirus Infections*
  • Uterine Cervical Dysplasia* / virology
  • Uterine Cervical Neoplasms* / virology

Substances

  • Immunologic Factors