Highlights and hot topics in GPCR research from 'Down Under'

Nicola J Smith; Lauren T May; Natasha L Grimsey

doi:10.1111/bph.16419

Highlights and hot topics in GPCR research from 'Down Under'

Br J Pharmacol. 2024 Jul;181(14):2091-2094. doi: 10.1111/bph.16419. Epub 2024 May 26.

Authors

Nicola J Smith¹, Lauren T May², Natasha L Grimsey^{3

4

5}

Affiliations

¹ Orphan Receptor Laboratory, School of Biomedical Sciences, UNSW Sydney, Sydney, Australia.
² Cardiac GPCR Laboratory, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Australia.
³ Department of Pharmacology and Clinical Pharmacology, School of Medical Sciences, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
⁴ Centre for Brain Research, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
⁵ Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand.

PMID: 38798136
DOI: 10.1111/bph.16419

Abstract

This article is part of a themed issue Therapeutic Targeting of G Protein-Coupled Receptors: hot topics from the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists 2021 Virtual Annual Scientific Meeting. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v181.14/issuetoc.

Keywords: G protein; G protein‐coupled receptors (GPCRs); PROTAC; allostery; artificial intelligence; cardiometabolic; cardiovascular; disease mechanisms; effectors; epilepsy; fibrosis; orphan; phosphoproteomics; regulation; schizophrenia; second messengers.

Publication types

Editorial
Introductory Journal Article

MeSH terms

Animals
Humans
Receptors, G-Protein-Coupled* / metabolism

Substances

Receptors, G-Protein-Coupled