French national protocol for diagnosis and management of epidermal necrolysis in adults (Stevens-Johnson syndrome and toxic epidermal necrolysis)

S Ingen-Housz-Oro; I Matei; A Gaillet; J Gueudry; K Zaghbib; H Assier; C Hua; B Bensaid; A Colin; R Ouedraogo; J Redlich; E Courtois; K Chazelas; E Sbidian; L Nakad; E Bequignon; N Terkmane; F Gaultier; F Schlemmer; G Do-Pham; A Barbaud; B Lebrun-Vignes; C Hoffmann; P-J Mahé; R Le Floch; C Bernier; B Vabres; B Milpied; A Delcampe; F Tétart; M Tauber; D Staumont-Sallé; F Dezoteux; V Descamps; L Misery; A-C Bursztejn; O Dereure; E Amazan; E Le Bidre; S Le Pallec; C Lagier; A Laroche; E Ferrat; P Wolkenstein; N de Prost; French National Reference Center for Toxic Bullous Diseases and Severe Drug Reactions TOXIBUL

doi:10.1016/j.annder.2024.103282

French national protocol for diagnosis and management of epidermal necrolysis in adults (Stevens-Johnson syndrome and toxic epidermal necrolysis)

Ann Dermatol Venereol. 2024 Jun;151(2):103282. doi: 10.1016/j.annder.2024.103282. Epub 2024 May 28.

Authors

S Ingen-Housz-Oro¹, I Matei², A Gaillet³, J Gueudry⁴, K Zaghbib⁵, H Assier², C Hua², B Bensaid⁶, A Colin², R Ouedraogo³, J Redlich², E Courtois², K Chazelas², E Sbidian⁷, L Nakad⁸, E Bequignon⁹, N Terkmane¹⁰, F Gaultier¹¹, F Schlemmer¹², G Do-Pham¹³, A Barbaud¹⁴, B Lebrun-Vignes¹⁵, C Hoffmann¹⁶, P-J Mahé¹⁷, R Le Floch¹⁷, C Bernier¹⁸, B Vabres¹⁹, B Milpied²⁰, A Delcampe⁴, F Tétart²¹, M Tauber²², D Staumont-Sallé²³, F Dezoteux²³, V Descamps²⁴, L Misery²⁵, A-C Bursztejn²⁶, O Dereure²⁷, E Amazan²⁸, E Le Bidre²⁹, S Le Pallec³⁰, C Lagier³⁰, A Laroche³⁰, E Ferrat³¹, P Wolkenstein³², N de Prost³³; French National Reference Center for Toxic Bullous Diseases and Severe Drug Reactions TOXIBUL³⁴

Affiliations

¹ Department of Dermatology, Henri Mondor, AP-HP, Créteil, France; Univ Paris Est Créteil EpiDermE, Créteil, France. Electronic address: [email protected].
² Department of Dermatology, Henri Mondor, AP-HP, Créteil, France.
³ Medical Intensive Care Unit, Henri Mondor Hospital, AP-HP, Créteil, France.
⁴ Department of Ophthalmology, Charles Nicolle University Hospital, Rouen, France.
⁵ Department of Psychiatry, Henri Mondor Hospital, AP-HP, Créteil, France.
⁶ Department of Dermatology, Edouard Herriot Hospital, Lyon, France.
⁷ Department of Dermatology, Henri Mondor, AP-HP, Créteil, France; Univ Paris Est Créteil EpiDermE, Créteil, France.
⁸ Emergency Department, Henri Mondor Hospital, AP-HP, Créteil, France.
⁹ Department of Otorhinolaryngology, Head and Neck Surgery, Créteil Intercommunal University Hospital, Créteil, France.
¹⁰ Department of Ophthalmology, Henri Mondor, AP-HP, Créteil, France.
¹¹ Department of Oral Medicine and Oral Surgery, Henri Mondor Hospital, AP-HP, Créteil, France.
¹² Department of Pneumology, Henri Mondor Hospital, AP-HP, Créteil, France.
¹³ Department of Internal Medicine, Centre Hospitalier Intercommunal de Créteil, Créteil, France.
¹⁴ Sorbonne Université, INSERM, Institut Pierre Louis d'Epidemiologie et de Sante Publique, AP-HP Sorbonne Universite, Tenon Hospital, Department of Dermatology and Allergology, Paris, France.
¹⁵ Regional Pharmacovigilance Centre, Pitié-Salpêtrière Hospital, APHP, Sorbonne Université, Paris, France.
¹⁶ Percy Military Hospital, Burn Center, Clamart, France.
¹⁷ Réanimation chirurgicale et des brûlés, PTMC, CHU Nantes, Nantes, France.
¹⁸ Department of Dermatology, CHU Nantes, Nantes, France.
¹⁹ Department of Ophthalmology, CHU Nantes, Nantes, France.
²⁰ Department of Dermatology, CHU Bordeaux, Bordeaux, France.
²¹ Department of Dermatology, Charles Nicolle University Hospital, Rouen, France.
²² Université Lyon 1/INSERM U1111 - CIRI/Hospices Civils de Lyon, Allergologie et Immunologie Clinique, CHU Lyon-Sud, Pierre-Benite France.
²³ Department of Dermatology, CHU Lille, Univ Lille, INSERM U1286, Lille Inflammation Translational Research Institute (INFINITE), Lille, France.
²⁴ Department of Dermatology, Bichat Hospital, AP-HP, Paris, France.
²⁵ Univ Brest, LIEN, Brest, France; University Hospital of Brest, Department of Dermatology, Venereology and Allergology, Brest, France.
²⁶ Department of Dermatology, CHU Nancy, Nancy, France.
²⁷ Department of Dermatology, INSERM U1058 « Pathogenesis and Control of Chronic Emerging Infections », University of Montpellier, Montpellier, France.
²⁸ Department of Dermatology, CHU Martinique, Fort de France, France.
²⁹ Department of Dermatology, University François Rabelais, Hospital of Tours, Tours, France.
³⁰ Patients' Association AMALYSTE, Paris, France.
³¹ University Paris-Est Créteil, INSERM, IMRB, Equipe CEpiA, Créteil, France.
³² Department of Dermatology, Henri Mondor, AP-HP, Créteil, France; University Paris-Est Créteil, UPEC, Créteil, France.
³³ Medical Intensive Care Unit, Henri Mondor Hospital, AP-HP, Créteil, France; University Paris-Est Créteil, UPEC, Créteil, France.
³⁴ French National Reference Center for Toxic Bullous Diseases and Severe Drug Reactions TOXIBUL, Filière FIMARAD, Créteil, France.

PMID: 38810539
DOI: 10.1016/j.annder.2024.103282

No abstract available

Keywords: Epidermal necrolysis; Guidelines; Management; Stevens-Johnson syndrome; Toxic epidermal necrolysis.

Publication types

Practice Guideline

MeSH terms

Adult
Clinical Protocols
France
Humans
Stevens-Johnson Syndrome* / diagnosis
Stevens-Johnson Syndrome* / etiology
Stevens-Johnson Syndrome* / therapy