Imaging of Solid Pulmonary Nodules

Clin Chest Med. 2024 Jun;45(2):249-261. doi: 10.1016/j.ccm.2023.08.013. Epub 2023 Sep 19.

Abstract

Early detection with accurate classification of solid pulmonary nodules is critical in reducing lung cancer morbidity and mortality. Computed tomography (CT) remains the most widely used imaging examination for pulmonary nodule evaluation; however, other imaging modalities, such as PET/CT and MRI, are increasingly used for nodule characterization. Current advances in solid nodule imaging are largely due to developments in machine learning, including automated nodule segmentation and computer-aided detection. This review explores current multi-modality solid pulmonary nodule detection and characterization with discussion of radiomics and risk prediction models.

Keywords: Computed tomography (CT); Computer-aided detection (CADe); Machine learning (ML); Magnetic resonance imaging (MRI); Radiomics; Risk prediction models; Segmentation; Solid nodule.

Publication types

  • Review

MeSH terms

  • Early Detection of Cancer / methods
  • Humans
  • Lung Neoplasms* / diagnosis
  • Lung Neoplasms* / diagnostic imaging
  • Lung Neoplasms* / pathology
  • Magnetic Resonance Imaging
  • Multiple Pulmonary Nodules / diagnostic imaging
  • Positron Emission Tomography Computed Tomography
  • Solitary Pulmonary Nodule* / diagnostic imaging
  • Tomography, X-Ray Computed*