Serum Ferritin Levels in Very Preterm Infants Receiving Erythrocyte Transfusions: A Retrospective Study

Indian Pediatr. 2024 Jul 15;61(7):668-670. Epub 2024 Jun 7.

Abstract

Very preterm infants often need red blood cell transfusions (RBCT) during intensive care and are at risk of iron overload. This study reviewed the records of 65 very preterm neonates who required at least one RBCT to ascertain the iron status using serum ferritin levels at 4-6 weeks age before oral iron was commenced. High serum ferritin level was found in 52.3% (n = 34) neonates. Need for > 1RBCT was significantly and independently associated with iron excess (P < 0.001). Increased ferritin noted following transfusions in neonatal period can have implications for determining the appropriate time for starting iron supplementation in this subgroup of neonates.

MeSH terms

  • Erythrocyte Transfusion* / methods
  • Female
  • Ferritins* / blood
  • Humans
  • Infant, Newborn
  • Infant, Premature* / blood
  • Iron / blood
  • Iron Overload / blood
  • Male
  • Retrospective Studies

Substances

  • Ferritins
  • Iron