Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of myocardial infarction that most frequently affects younger women, making it an important cause of morbidity and mortality within these demographics. The evolution of intracoronary imaging, improved diagnosis with coronary angiography, and ongoing research efforts and attention via social media, has led to increasing recognition of this previously underdiagnosed condition. In this review, we provide a summary of the current body of knowledge, as well as focused updates on the pathogenesis of SCAD, insights on genetic susceptibility, contemporary diagnostic tools, and immediate, short- and long-term management.
Keywords: FMD—fibromuscular dysplasia; IVUS—intravascular ultrasound; NSTEMI—non‐ST elevation myocardial infarction; OCT—optical coherence tomography; SCAD—spontaneous coronary artery dissection; STEMI—ST‐elevation myocardial infarction.
© 2024 The Authors. Clinical Cardiology published by Wiley Periodicals, LLC.