A challenging case of aggressive composite hemangioendothelioma with neuroendocrine differentiation and PTBP1::MAML2 fusion

Christophe Bontoux; Anna Vigier; Thibaud Valentin; Charlotte Syrykh; Aurore Siegfried; Céline Basset; Jean Mourlanette; Hadrien Reboul; Solène Evrard; Anne Gomez-Mascard

doi:10.1002/gcc.23245

A challenging case of aggressive composite hemangioendothelioma with neuroendocrine differentiation and PTBP1::MAML2 fusion

Genes Chromosomes Cancer. 2024 Jun;63(6):e23245. doi: 10.1002/gcc.23245.

Authors

Christophe Bontoux^{1

2

3

4}, Anna Vigier^{1

2}, Thibaud Valentin^{3

5}, Charlotte Syrykh^{1

2}, Aurore Siegfried^{1

2}, Céline Basset^{1

2}, Jean Mourlanette^{2

6}, Hadrien Reboul^{1

2}, Solène Evrard^{1

2}, Anne Gomez-Mascard^{1

2

3

4}

Affiliations

¹ Department of Pathology, Cancer University Institute of Toulouse-Oncopole, University Hospital of Toulouse, Toulouse, France.
² University of Toulouse III Paul Sabatier, Toulouse, France.
³ OncoSarc, INSERM U1037, Cancer Research Center in Toulouse, Toulouse, France.
⁴ Cancer Biobank, Cancer University Institute of Toulouse-Oncopole, Toulouse, France.
⁵ Department of Medical Oncology, Cancer University Institute of Toulouse-Oncopole, Toulouse, France.
⁶ Thoracic Oncology Department, Larrey Hospital, University Hospital of Toulouse, Toulouse, France.

PMID: 38861371
DOI: 10.1002/gcc.23245

No abstract available

Publication types

Letter
Comment

MeSH terms

Cell Differentiation / genetics
DNA-Binding Proteins / genetics
Female
Hemangioendothelioma* / genetics
Hemangioendothelioma* / pathology
Heterogeneous-Nuclear Ribonucleoproteins / genetics
Humans
Male
Oncogene Proteins, Fusion* / genetics
Polypyrimidine Tract-Binding Protein / genetics
Polypyrimidine Tract-Binding Protein / metabolism
Trans-Activators* / genetics
Transcription Factors / genetics

Substances

MAML2 protein, human
Trans-Activators
Oncogene Proteins, Fusion
Polypyrimidine Tract-Binding Protein
Heterogeneous-Nuclear Ribonucleoproteins
Transcription Factors
DNA-Binding Proteins